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After2 weeks of flucloxacillin (4 ? 2 g i.v./day) followed by 4 weeks of oral levofloxacin (1 ?750 mg/day) plus rifampin (2 ? 300 mg/day), antibiotics were stopped. A syno-vial fluid leukocyte count of more than 1700/µl or a differential count of more than 65%neutrophils is consistent with infection of knee arthroplasties that have been in place forat least 6 months in subjects without inflammatory joint diseases [40]. The fact that they are time-locked to an artifi-cial stimulus allows them to be averaged over hundreds of trials, dramatically boosting theirSNR even in electronically noisy ICU environments (7). However, crocodilians have a nonmusculartissue which functions as a rudimentary diaphragm

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Practice parameter: prediction of outcome in comatosesurvivors after cardiopulmonary resuscitation (an evidence-based review): report of the Qual-ity Standards Subcommittee of the American Academy of Neurology. This resulted in a meantime of 43 h from ICU admission to the ? rst pro-tocol intervention unlike those patients in theearly goal-directed therapy studies where themean time to treatment was 1.5 h after arrival tothe emergency room.

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The IDSA guidelines consider definitive PJIto be present if there is a sinus tract communicating with the prosthesis, purulence withoutanother known etiology surrounding the prosthesis, or two or more cultures yielding thesame organism; the presence of acute inflammation on histopathological examination ofperiprosthetic tissue is considered highly suggestive of PJI [32]. This test is useful in the diagnosis and formonitoring the efficacy of eradication.

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